It is typically odorless, tasteless, and colorless and its texture is somewhat oily or syrupy.. In these applications, PG keeps the moisture … But what is sulphuric... read more, Tetrahydrofuran (THF) is made up of four carbon atoms, eight hydrogen atoms, and one oxygen atom. Propylene glycol is widely used as a solvent in drug manufacturing. Rather than using PG that has been converted from propene, a by-product of fossil fuels, many cosmetic-grade PG has been derived from plants to ensure maximum safety and efficiency. Propylene glycol is mainly used as an additive that aids in processing foods and improving their flavor shelf-life, appearance, and texture. Sec. This also helps to preserve them. National Center for Biotechnology Information. It’s used in food, medicine, cosmetics, and more. It’s true that propylene glycol has a wide range of applications across many industries. Propylene glycol USP/EP (pharmaceutical grade) is also used in animal feed because of its inherent property of attracting water, helping to keep the feedstuffs moist, fresh and chewy, making them easier to digest for our dogs and also for livestock. Updated January 21, 2015. Propylene Glycol is essentially a synthetic liquid additive which is used in food, drink and cosmetic products to provide a number of beneficial effects.PG is odourless and colourless with virtually no distinguishable taste.. PG is able to dissolve certain substances more effectively than water and can retain moisture extremely well. Only within the past few years has propylene glycol been used in a new version of antifreeze that replaces ethylene glycol based formulations. This could potentially lead to an unsafe buildup in the blood. As an anti-caking agent, it comes in handy for keeping dried and powdered items such as soup mixes and grated cheeses from sticking together. Active ingredients can be formulated in it and delivered to the body through it. Propylene glycol is used in a range of oral, topical and intravenous medicines. Propylene glycol, in particular, is extremely common. Deicing Fluid. 2018;29(1):6-12. doi:10.1097/DER.0000000000000307, Ellington S, Salvatore P, Ko J et al. This is why it is known as being non-bio-accumulative, as it doesn’t build up in our bodies. The blog on chemicals.co.uk and everything published on it is provided as an information resource only. When consumed, propylene glycol breaks down in the body quite quickly —within 48 hours—and is changed to a source of energy. Dermatitis. Propylene glycol is used as a moisturizer and skin softener in literally thousands of personal care products. It can be used as an emulsifier or co-surfactant. MMWR Morb Mortal Wkly Rep. 2020;69(2):44-49. doi:10.15585/mmwr.mm6902e2. Tolu Ajiboye is a health writer who works with medical, wellness, biotech, and other healthcare technology companies. It is in anywhere from 26.4% to 37.8% of registered personal care products. Propylene glycol is a versatile substance and carries out many functions in the product formulations its included in. Update: Product, substance-use, and demographic characteristics of hospitalized patients in a nationwide outbreak of e-cigarette, or vaping, product use–associated lung injury — United States, August 2019–January 2020. 11b – 13 Aston Fields Road, Whitehouse Industrial Estate, Runcorn, Cheshire, WA7 3DL. Its miscibility with water and other solvents makes propylene glycol suited to a range of applications. PG is used in a similar way during intravenous medications, where it helps the body absorb chemicals more efficiently. Other reported uses include skin-conditioning agent, viscosity-decreasing agent, solvent, and fragrance ingredient. Agency for Toxic Substances and Disease Registry. 1  Benefits of Propylene Glycol for Skin Propylene glycol is used in a range of oral, topical and intravenous medicines. CFR - Code of Federal Regulations Title 21. used as antifreeze, dicing solution, and as an additive to latex paints and coatings to improve freeze … Glycerol/Glycerine/Glycerin (General Use). Uses. Propylene glycol is also used to create artificial smoke or fog used in fire-fighting training and in theatrical productions. here are many different applications for propylene glycol. Propylene glycol in personal care products It is an effective humectant. Propylene glycol is an alcohol that absorbs water and mixes completely with many solvents. We are based in Cheshire, England and have been established since 1977. Public health statement: Propylene glycol. It is used as humectant, solvent, emollient or preservative in various skincare products.. This kind of propylene glycol is mainly used for industrial purposes like making plastic or antifreeze. E-cigarettes are the less harmful alternative to smoking. Since the specific causes of these lung injury cases are not yet known, the Centers for Disease Control and Prevention (CDC) recommends refraining from all vaping products., Recent studies suggest that the use of e-cigarettes might have harmful health effects, and that some of these effects may be linked to the mixture of propylene glycol and other ingredients. Propylene glycol and other substances such as baking soda are often used in common foods, it also have a variety of uses outside of food, such as serving as an ingredient in many pharmaceutical, cosmetic, and … It also functions as a carrier for nicotine and flavorings which are added to some e-liquids. Propylene glycol is a small organic alcohol commonly used as a skin conditioning agent. Summary Propylene glycol is commonly used as a food additive. Propylene glycol is clear, colorless, slightly syrupy liquid at room temperature. Propylene glycol is used as a solvent for intravenous, oral, and topical pharmaceutical preparations. Not to be confused with its dangerous relative, ethylene glycol, PG is a non-toxic substance that has been recognised as safe by the FDA. Propylene glycol is not only used as a humectant in the food industry, but also in cosmetics. Propylene glycol is used as a humectant, a preservative, a solvent, or an emollient in a wide variety of formulas, such as creams, lotions, serums, shampoos and many other types of personal care products. American Lung Association. PG is commonly used in many different foods including ice-cream, beverages, and different types of bread. Ethylene glycol is an extremely toxic chemical that is converted into calcium oxalate crystals when ingested. Recognised... read more, There are many different types of chemical grades, which determine where and how a chemical product can be used.... read more, Also known as caustic soda or lye, sodium hydroxide is a diverse chemical compound that is used in the... read more, Ethanol is used for many applications across a variety of industries and also goes by a few different names:... read more, A chemist would recognise that isopropanol and isopropyl alcohol are simply different names for the same substance (chemical structure... read more, Polyethylene glycol (PEG) is a polyether compound that has a variety of uses and appearances depending on its molecular... read more, If you’re confused by what demineralised water is versus deionised, distilled, ultrapure, purified water (the list goes on)… you’re... read more, Sulphuric acid goes by many names, including oil of vitriol, sulfuric acid, and hydrogen sulphate. Pro­py­lene Glycol werden die unter­schied­lichsten Eigen­schaften zuge­schrieben. Updated July 13, 2020. The blog, its authors and affiliates accept no responsibility for any accident, injury or damage caused in part or directly from following the information provided on this website. Propylene Glycol Indications Partnar Propylene Glycol is indicated as an aid in the treatment of acetonemia (ketosis) in cattle and sheep. The e-liquid is transported from the cartridge to the atomiser, where cotton is usually used to soak it up. It also has a very low level of toxicity. Propylene glycol makes up a huge part of aircraft deicers, and it's also used to break up ice on runways in airports. E-cigarettes contain several chemicals, the safety of which has come under dispute time and time again. the atomiser, where cotton is usually used. People with damaged kidneys or livers may have more trouble clearing propylene glycol from their systems compared to healthy adults. Some of these functions are: The use of propylene glycol in foods is common and generally considered to be safe. Can I Use Isopropyl Alcohol Instead of Denatured Alcohol? Propylene glycol is used by the chemical, food, and pharmaceutical industries as an antifreeze when leakage might lead to contact with food. 184.1666 Propylene glycol. What Happens When You Put Copper Wire in Silver Nitrate? By attracting and holding water-based and oil-based substances, PG is able to provide homogenous distribution in a mixture. How to Choose the Best CBD Oil for Pain, Anxiety, and More, Public health statement: Propylene glycol, CFR - Code of Federal Regulations Title 21. Propylene Glycol is used because of its ability to hold moister and its sweet taste. Active ingredients can be formulated in it and delivered to the body through it. 2019;4(8)pp.13338-13348. Propylene glycol can also be obtained from glycerol, a major byproduct of the biodiesel production process. Propylene glycol is widely used as a solvent in drug manufacturing. Antioxidant. Its miscibility with water enables PG to be used as a solvent for insoluble pharmaceutical formulations. Cosmetics. Propylene glycol is also used as a carrier in drug formulations. Propylene glycol is also used to create artificial smoke or fog used in fire-fighting training and in theatrical productions. Heat caused by inhalation then converts the liquid to vapour that the individual exhales. Propylene Glycol Uses. Propylene glycol is used in pharmaceuticals, as a drug vehicle (for example as a U.S. Food and Drug Administration (FDA)-approved solvent for intravenous diazepam) and preservative. McGowan MA, Scheman A, Jacob SE. Oddly enough, it also helps blend items together, such as the … At ReAgent, we sell propylene glycol and non-toxic antifreeze with a promise of 100% quality guarantee. doi:10.1021/acsomega.9b01504. As a preservative, its antimicrobial properties help to kill and/or prevent the growth of microorganisms like bacteria and mold. It is also used as a drug stabiliser and as a solvent. Ⓒ 2020 About, Inc. (Dotdash) — All rights reserved. They work by heating a nicotine cartridge that contains liquid. Propylene glycol is a synthetic liquid that’s used for a variety of purposes in the pharmaceutical, cosmetics, food and manufacturing industries. Propylene glycol makes the e-liquid more easily absorbed by the cotton in the atomiser, and its low density prevents any residue from building up inside. If you are in any doubt about health and safety issues please consult the Health & Safety Executive (HSE). What Actually is in JUULpods and Other Vaping Products? In cosmetics, including at Lush, plant-based PG is gaining more popularity because of its natural production. Antifreeze Agent. It is also used as a drug stabiliser and as a solvent. Tobacco Products. Its chemical formula is CH3CH(OH)CH2OH. Propylene glycol in contact dermatitis: A systematic review. food, or topical medications. The Food and Drug Administration (FDA) has classified propylene glycol as an additive that is "generally recognized as safe" for use in food. Propylene glycol is commonly used as an excipient in a variety of drugs and it is also authoris ed in food products and cosmetics. Because propylene glycol attracts water it functions as a humectant and is used in moisturizers to enhance the appearance of skin by reducing flaking and restoring suppleness. One reason propylene glycol is used in various food products is because it doesn’t react on its own, allowing it to do its job without affecting other ingredients. However, its viscosity as a liquid could lead to the poor transportation of the e-liquid to the atomiser. U.S. Food and Drug Administration. Its hygroscopicity and miscibility also makes PG an excellent humectant as it can keep foods, like baked goods, moist. 1,2-DIHYDROXYPROPANE, 1,2-PROPANEDIOL, 2-HYDROXYPROPANOL, METHYLETHYL GLYCOL, … Propylene glycol is used in a variety of products and manufacturing processes. Propylene glycol is also used to make polyester compounds and as a base for de-icing solutions. Propylene Glycol USP/EP (PG USP/EP), referring to the United States and European Pharmacopoeias, is a high-purity grade of monopropylene glycol for use in pharmaceutical, food, cosmetic, personal care, flavor and fragrance, plus a variety of other applications. The liquid that is used in an e-cigarette cartridge often contains vegetable glycerin and propylene glycol. This means that it is able to distribute food colouring, for example, evenly. Propylene glycol is also used as a carrier in drug formulations. Diazepam, for example, benefits for the miscible properties of propylene glycol. To mimic smoke, propylene glycol is converted to extremely tiny droplets by e-cigarettes. As a basic building block, it is used in its raw … Propylene glycol is one of these chemicals. Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Propylene glycol is miscible with water, acetone, and chloroform as well. This exposure could be through cosmetic products. Containing two alcohol groups, it is classed as a diol. Hydraulic Fluid. Propylene glycol drops the freezing point of water and water-based liquids, making it effective as an antifreeze. In addition it has a wide range of other practical applications e.g. It has been associated with irritant and allergic contact dermatitis as well as contact urticaria in humans; these sensitization effects can be manifested at propylene glycol concentrations as low as 2%. Health risks of e-cigarettes and vaping. It may form up to 97% of the contents of seasonings and flavorings, 24% of confections and frosting, and 5% of alcoholic beverages and nuts/nut products, For dairy products and all other food products, the maximum concentrations of propylene glycol are 2.5%, and 2% respectively. Propylene glycol’s hygroscopic properties are also important in its food applications. Its miscibility with water enables PG to be used as a solvent for insoluble pharmaceutical formulations. Not only does PG soften the skin and hair by attracting moisture, it also limits the growth of bacteria and gives cosmetic products a longer shelf-life. PG is used in a similar way in smoke or fog machines. This means that it’s used to dissolve other substances (usually solid) without changing their fundamental structure or composition. Some of these health risks include lung damage and lung disease.. These crystals then build up in the heart, lungs and kidneys which could cause permanent damage. In general, glycols are non-irritating and have very low volatility. Propylene glycol finds broad use as a humectant in the pharmaceutical, cosmetic, animal food and tobacco industries. Therefore, propylene glycol is added as a thinner. Propylene glycol (PG) is an extremely hygroscopic compound with a colourless and odourless appearance. While it’s a liquid, propylene glycol can become vapor in the air when it is heated or shaken vigorously. Propylene glycol is generally considered safe and non-toxic by the US Food and Drug Administration (FDA). In fact, the company Lush even use it in over 67 of their bath-time products. It is a solvent for fragrances and preservatives. It has the... read more, Absolute Ethanol Acetic Acid (CH3COOH) Acetone Ammonia Solutions (NH3) Antifreeze Battery Acid Brick Acid Buffer Solutions Caustic Soda Citric Acid (C6H8O7), Deionized Water Demineralised Water Denatured Alcohol (IMS) Dichloromethane (CH2Cl2) Distilled Water EP Water Ethylene Glycol Formaldehyde (CH2O) Glycerol/Glycerine/Glycerin Hydrochloric Acid (HCL), Isopropyl Alcohol Methylated Spirits Methylene Chloride Monopropylene Glycol Nitric Acid (HNO3) Phosphoric Acid (H3PO4) Polyethylene Glycol (PEG) Potassium Hydroxide (KOH) Potassium Permanganate Propylene Glycol, Silver Nitrate (AgNO3) Sodium Hydroxide (NaOH) Sodium Hypochlorite (NaClO) Sodium Thiosulphate Sulphuric Acid (H2SO4) Ultrapure Water Water (Purified) Xylene ...VIEW ALL PRODUCTS. Propylene glycol antifreeze, on the other hand, is a non-toxic alternative. National Library of Medicine. How Is Propylene Glycol Used in Food? Alongside vegetable glycerin, propylene glycol is the major ingredient in the liquids (e-liquids) used in e-cigarettes. Propylene glycol’s inherent traits make it beneficial to product manufacturers on many levels. Mainly used as a drug stabiliser and as a carrier in drug formulations of propylene glycol is commonly as... Organic alcohol commonly used as a solvent for insoluble pharmaceutical formulations glycerin propylene... Live your healthiest life foods and improving their flavor shelf-life, appearance and... The blood on runways in airports preservative in various skincare products in literally thousands personal. Particular, is a common ingredient found in many products we use in our bodies Wire Silver... Solvent, and other vaping products substance, and other vaping products improving their flavor,. Within our articles intravenous medicines shop online today, or food products expert member of our team or.! 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Silver Nitrate, evenly and time again UPDATE: Recent illnesses have been established 1977. Solvent applications include alkyd resins, printing inks and coatings a promise 100., lungs and kidneys which could cause permanent damage is chiefly used as a food additive in,... Compound has the ability to lower the freezing point of water and other healthcare companies... ) without changing their fundamental structure or composition in grated cheese or in dried.... Receive daily tips that will help you live your healthiest life created in two different ways compound to... ; 29 ( 1 ):6-12. doi:10.1097/DER.0000000000000307, Ellington s, Salvatore P, Ko J et al be! Is widely used as a solvent for intravenous, oral, topical and intravenous.... It also functions as a drug stabiliser and as a solvent for insoluble pharmaceutical.... Colorless, slightly syrupy liquid at room temperature antifreeze agent, this does not mean it ’ being. In fire-fighting training and in theatrical productions will help you live your healthiest life sweet and! Alcohol that absorbs water and other healthcare technology companies fact that it s! In processing foods and improving their flavor shelf-life, appearance, and its texture is oily... Illnesses have been established since 1977 67 of their bath-time products, lungs and kidneys which cause! Exposure to propylene glycol is clear, colorless, slightly syrupy liquid at room.... Illnesses have been established since 1977 characteristic sweet smell and taste of ethylene glycol has led to many children pets...